|
|
|
|
|
|
|
||
| ||||||||||||||||||||||||||
Index of Online Supplemental Material for
J. Exp. Med. 10.1084/jem.20061864
DeVoss et al. • Figure S1 C57BL/6 x NOD F2 aire-deficient mice have a limited autoreactive repertoire and predominantly recognize IRBP.
• Figure S2 Immunoblot of eluates from immunoaffinity purification with aire-deficient and aire-sufficient sera.
• Figure S3 Provisional identification of IRBP as the 150-kD autoantigen by PMF.
• Figure S4 Indirect immunofluorescence using aire-deficient sera on frozen sections of IRBP-sufficient or IRBP-deficient eye.
• Figure S5 Increased precursor frequency of IRBP-specific T cells in aire-deficient mice.
• Figure S6 Absence of ocular autoimmunity in some C57BL/6 aire-deficient animals.
• Figure S7 Autoimmunity in lacrimal glands of both aire-deficient and aire- and IRBP-deficient (DKO) mice.
• Figure S8 Flow cytometry analysis of cells from the eyes of aire-deficient and aire- and IRBP-deficient (DKO) mice.
• Figure S9 Flow cytometry analysis of cells from IRBP-deficient and IRBP-sufficient thymic stromal recipients.
• Table S1 Analysis of CD4- and CD8-depleted adoptive transfer experiments
• Table S2 Real-time PCR primers and probes for analysis of aire-regulated genes
• Supplemental text (PDF)
| ||||||||||||||||||||||||||
| TABLE OF CONTENTS |
|
