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Index of Online Supplemental Material for
J. Exp. Med. 10.1084/jem.20061293
Schleicher et al. Figure S1 Up-regulation of costimulatory molecules and induction of IFN-α/β in pDCs.
Figure S2 Expression of IFN-α4, IFN-β, and IFN-γ mRNA in the spleens of infected versus uninfected C57BL/6 WT and IFNAR-/- mice injected i.v. with 107 L. infantum promastigotes.
Figure S3 Significantly reduced IFN-α production in pDC-depleted mice after i.v. injection of CpG.
Figure S4 Cytokine expression in the spleens of DT-treated C57BL/6 WT and CD11c-DTR/GFP transgenic mice 2 d after injection of DT.
Figure S5 Percentage of NK cells in the spleens of C57BL/6 and CD11c-DTR/GFP transgenic mice 2 d after i.p. injection of DT and 24 h after i.v. infection with 107 L. infantum promastigotes or control injection of PBS.
Figure S6 Linear regression analysis of NK cell cytotoxicity and DC reconstitution in C57BL/6 and CD11c-DTR/GFP transgenic mice 5 d after i.p. injection of DT and 12-24 h after i.v. infection with 107 L. infantum promastigotes.
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