The Journal of Experimental Medicine
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Index of Online Supplemental Material for
J. Exp. Med. 10.1084/jem.20041392
Winter et al.

Figure S1 The SURFIN4.2-encoding PFD1160w gene, also referred to as 3D7surf4.2, is identified by peptides released by the mild trypsinization of live cells.

Figure S2 The CRD in the variable domain of SURFIN and PvSTP1 is related to the cysteine-rich variable region encoded by vir genes.

Figure S3 The WRD domains of SURFINs/PvSTP1 feature structural segments found in the internal domains of other exported and surface-exposed proteins of human, monkey, and rodent parasites.

Figure S4 Relation of the SURFIN WRD S2 segments and S2 in the conserved ATS of PfEMP1.

Figure S5 Position of 13 annotated ORFs constituting 10 surf genes in the 3D7 genome.

Figure S6 Schematic outline of the surf gene family.

Figure S7 Merozoite invasion inhibition assay in presence of anti-rSURFIN4.2 antibody.

Figure S8 Model of SURFIN, RIFIN, and PfEMP1 expression in blood stages.

Figure S9 SURFINs show genotypic polymorphism but are not phenotypic switch variants.





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