The Journal of Experimental Medicine
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The Journal of Experimental Medicine, Vol 62, 517-521, Copyright, 1935, by The Rockefeller Institute for Medical Research New York

ARTICLE

INACTIVATION OF POLIOMYELITIS VIRUS IN VITRO BY CRYSTALLINE VITAMIN C (ASCORBIC ACID)

Claus W. Jungeblut M.D.1

1 From the Department of Bacteriology, College of Physicians and Surgeons, Columbia University, New York

The experimental evidence presented in this paper shows that multiple paralytic doses of poliomyelitis virus, when mixed with very small amounts of crystalline vitamin C (ascorbic acid), are rendered non-infectious as determined by intracerebral injection of such mixtures into rhesus monkeys.

Submitted on July 2, 1935


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