The Journal of Experimental Medicine
Avanti Polar Lipids, Inc.
  Home | Help | Feedback | Subscriptions | Archive | Search | Table of Contents
This Article
Right arrow Full Text (PDF, 807K)
Right arrow Alert me when this article is cited
Services
Right arrow Email this article
Right arrow Similar articles in this journal
Right arrow Alert me to new content in the JEM
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Miller, D. K.
Right arrow Articles by Rhoads, C. P.
Right arrow Search for Related Content
PubMed
Right arrow Articles by Miller, D. K.
Right arrow Articles by Rhoads, C. P.
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Facebook   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?
The Journal of Experimental Medicine, Vol 59, 315-331, Copyright, 1934, by The Rockefeller Institute for Medical Research New York

ARTICLE

THE VITAMIN B1 AND B2 G CONTENT OF LIVER EXTRACT AND BREWERS' YEAST CONCENTRATE

D. K. Miller M.D.1 and C. P. Rhoads M.D.1

1 From the Hospital of The Rockefeller Institute for Medical Research

1. Liver extract powder, No. 343 Lilly, and the same material prepared for parenteral use, when administered daily by mouth in amounts derived from 2.5 gm. of fresh whole liver, to rats weighing from 40 to 50 gm., contain sufficient vitamin B1 to support normal growth, provided the animals receive in addition an adequate amount of vitamin B2 G. Moreover, liver extract in the forms mentioned, administered in the same amounts, does not contain sufficient vitamin B2 G to maintain normal growth of similar rate when all other necessary constituents of the diet are provided.

2. Liver extract (Lilly) in the form prepared for parenteral use, when administered daily by intraperitoneal injections, in amounts derived from 2.5 gm. of fresh whole liver, to rats under standard experimental conditions, does not contain sufficient vitamin B2 G to maintain normal growth. Furthermore, the amount of vitamin B1 present in liver extract in this form is not as effective in supporting normal growth when given by intraperitoneal injection as it is when given by mouth.

3. Vegex, when administered daily in amounts of 50, 150, and 250 mg. to rats of 40 to 50 gm. in weight contains sufficient vitamin B1 to maintain normal growth of the rats, provided the animals receive in addition an adequate amount of vitamin B2 G. However, vegex in the same amounts does not contain sufficient vitamin B2 G to support normal growth of similar rats when all other necessary constituents of the diet are provided.

4. These experiments indicate that the extrinsic, anti-anemic factor of Castle and the thermostable growth-promoting food constituent, commonly known as vitamin B2 G, are not identical.

 Submitted on November 26, 1933


Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Facebook Facebook   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter    What's this?


This article has been cited by other articles:



  Home | Help | Feedback | Subscriptions | Archive | Search
TABLE OF CONTENTS