The Journal of Experimental Medicine
VeriKine-HS Human IFN-Beta
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The Journal of Experimental Medicine, Vol 53, 143-150, Copyright, 1931, by The Rockefeller Institute for Medical Research New York

ARTICLE

ABSORPTION FROM THE PERICARDIAL CAVITY

Cecil K. Drinker M.D.1 and Madeleine E. Field 1

1 From the Department of Physiology, Harvard School of Public Health, Boston

1. Physiological salt solution is absorbed from the pericardial cavity of medium-sized rabbits at a rate of approximately 1.3 cc. per hour. This absorption is via the subepicardial blood capillaries.

2. Rabbit serum and horse serum are absorbed extremely slowly—an indication of the low-grade lymphatic drainage of the pericardial sac.

3. Graphite particles of bacterial dimensions are also removed very slowly. Such particles enter lymphatics only after phagocytosis. The lymphatics in the basal part of the pericardium are the principal source of drainage. Subepicardial lymphatics are entered with difficulty from the pericardial cavity.

 Submitted on September 19, 1930


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