The Journal of Experimental Medicine
Torrey Pines Biolabs
  Home | Help | Feedback | Subscriptions | Archive | Search | Table of Contents
This Article
Right arrow Full Text (PDF, 820K)
Right arrow Alert me when this article is cited
Services
Right arrow Email this article
Right arrow Similar articles in this journal
Right arrow Alert me to new content in the JEM
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by MacKay, E.
Right arrow Articles by Oliver, J.
Right arrow Search for Related Content
PubMed
Right arrow Articles by MacKay, E.
Right arrow Articles by Oliver, J.
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Facebook   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?
The Journal of Experimental Medicine, Vol 51, 161-178, Copyright, 1930, by The Rockefeller Institute for Medical Research New York

ARTICLE

A COMPARISON OF THE METHOD OF EXCRETION OF NEUTRAL RED AND PHENOL RED BY THE MAMMALIAN KIDNEY

Eaton MacKay M.D.1 and Jean Oliver M.D.1

1 From the Departments of Medicine and Pathology of the Stanford University Medical School, San Francisco

A direct examination with the method of perfusion of the excretion by the frog's kidney of phenol red and neutral red has shown that the dyes are eliminated in different manners as a result of different mechanisms. The former is excreted in much the greater part by the glomeruli; the latter by the tubules. Urea is excreted in a manner similar to phenol red.

The indirect examination of the function of the mammalian kidney by means of excretion ratios has shown a like contrast between the manner of elimination of the two dyes, and here again was found a similarity in the manner of excretion of phenol red and urea.

This would seem to be as close an examination as can be made with our present methods of experimentation of the question of the mechanism of the excretion of these substances by mammals. As the facts stand they constitute strong presumptive evidence that in mammals and amphibia the like results have arisen from like causes, phenol red and urea being eliminated chiefly through the glomeruli in both instances while neutral red is excreted principally through the tubules.

 Submitted on October 28, 1929


Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Facebook Facebook   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter    What's this?


This article has been cited by other articles:



  Home | Help | Feedback | Subscriptions | Archive | Search
TABLE OF CONTENTS