The Journal of Experimental Medicine
VeriKine-HS Human IFN-Beta
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The Journal of Experimental Medicine, Vol 50, 803-808, Copyright, 1929, by The Rockefeller Institute for Medical Research New York

ARTICLE

STUDIES ON YELLOW FEVER IN SOUTH AMERICA : V. TRANSMISSION EXPERIMENTS WITH CERTAIN SPECIES OF CULEX AND AËDES



Nelson C. Davis M.D.1 and Raymond C. Shannon 1

1 From the Yellow Fever Laboratory of the International Health Division of the Rockefeller Foundation, Bahia, Brazil

1. Yellow fever virus has been transmitted from monkey to monkey both by the bites of Aëdes (Ochlerotatus) scapularis which had fed upon monkeys infected with yellow fever and by the injection of the ground up bodies of such mosquitoes.

2. A fatal infection has been obtained by the injection of the ground up bodies of Aëdes (Ochlerotatus) serratus, which had previously fed on an infected monkey, and a mild infection has been secured by the similar injection of Aëdes (Taeniorhynchus) taeniorhynchus.

3. No definite infection has been secured either by the bites or by the injection of Culex quinquefasciatus (C. fatigans). However, some of the experimental animals bitten by this species have been relatively immune following inoculations of blood or tissues containing virus.

 Submitted on September 2, 1929


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