The Journal of Experimental Medicine
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The Journal of Experimental Medicine, Vol 50, 767-775, Copyright, 1929, by The Rockefeller Institute for Medical Research New York

ARTICLE

STUDIES ON THE DISSOCIATION OF THE HOG CHOLERA BACILLUS : III. ACTIVE IMMUNIZATION WITH R FORMS



C. P. Li M.D.1

1 From the Division of Bacteriology, Department of Pathology, Peking Union Medical College, Peiping, China

1. Heat killed organisms of the MS (OH), MR (ØH), NS (O) or NR (Ø) forms of hog cholera bacilli failed to confer immunity, at least to any considerable degree, in hamsters or rabbits against virulent hog cholera bacilli.

2. Hamsters and rabbits were successfully immunized against virulent MS bacilli by vaccination with living MR (ØH) and NR (Ø) forms.

3. Hamsters were immunized against MS hog cholera bacilli with living R paratyphoid "C" bacilli and conversely against MS paratyphoid "C" bacilli with living R hog cholera bacilli.

 Submitted on September 15, 1929


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