The Journal of Experimental Medicine
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The Journal of Experimental Medicine, Vol 50, 81-85, Copyright, 1929, by The Rockefeller Institute for Medical Research New York

ARTICLE

STUDIES ON SOUTH AMERICAN YELLOW FEVER : III. TRANSMISSION OF THE VIRUS TO BRAZILIAN MONKEYS PRELIMINARY OBSERVATIONS



Nelson C. Davis M.D.1 and Raymond C. Shannon 1

1 From the International Health Division of the Rockefeller Foundation, New York, and the Yellow Fever Laboratory, Bahia, Brazil

Yellow fever virus from M. rhesus has been inoculated into a South American monkey (Cebus macrocephalus) by blood injection and by bites of infected mosquitoes. The Cebus does not develop the clinical or pathological signs of yellow fever. Nevertheless, the virus persists in the Cebus for a time as shown by the typical symptoms and lesions which develop when the susceptible M. rhesus is inoculated from a Cebus by direct transfer of blood or by mosquito (A. aegypti) transmission.

Submitted on April 22, 1929


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