The Journal of Experimental Medicine
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The Journal of Experimental Medicine, Vol 50, 15-29, Copyright, 1929, by The Rockefeller Institute for Medical Research New York

ARTICLE

A COMPARISON OF THE MANNER OF EXCRETION OF NEUTRAL RED AND PHENOL RED BY THE FROG'S KIDNEY

Jean Oliver M.D.1 and Eshref Shevky Ph.D.1

1 From the Department of Pathology of Stanford University Medical School, San Francisco, California

1. Phenol red and neutral red are excreted by the perfused frog's kidney by different routes.

2. Phenol red is excreted chiefly through the glomerulus, neutral red through the tubules.

3. Some slight excretion of each of these dyes by the converse mechanism is possible, though there is no evidence in our experiments that necessitates such a conclusion.

4. The importance of methods leading to the production of a normal volume of urine by the perfused kidney is emphasized.

 Submitted on March 31, 1929


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