The Journal of Experimental Medicine
VeriKine-HS Human IFN-Beta
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Published online
doi:10.1084/jem.2049fta
The Journal of Experimental Medicine, Vol. 204, No. 9, 2013-
The Rockefeller University Press, 0022-1007 $30.00
© Bashyam
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From the Archive

 Uncovering the dark side of TNF

Hema Bashyam, JEM News Editor

hbashyam{at}rockefeller.edu


ABSTRACT
In the early 1980s, in search of the cytokine that triggers disease- associated weight loss and lethal shock, Anthony Cerami and Bruce Beutler purified "cachectin." They soon found out that their malevolent cytokine already had another name—tumor necrosis factor (TNF)—and was being lauded as a potential antitumor agent.

The Rockefeller University Press


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