The Journal of Experimental Medicine
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Published online
doi:10.1084/jem.20412fta
The Journal of Experimental Medicine, Vol. 204, No. 12, 2777-
The Rockefeller University Press, 0022-1007 $30.00
© Bashyam
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FROM THE ARCHIVE

 Lewis Thomas and droopy rabbit ears

Hema Bashyam, JEM News Editor

hbashyam{at}rockefeller.edu


ABSTRACT
In 1956, Lewis Thomas discovered that injecting rabbits with a plant protease called papain caused their ears to collapse. This experiment led to the identification of the endogenous proteases that cause the tissue destruction seen in diseases such as rheumatoid arthritis.


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