The Journal of Experimental Medicine
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Published online October 22, 2007
doi:10.1084/jem.20411fta
The Journal of Experimental Medicine, Vol. 204, No. 11, 2499-
The Rockefeller University Press, 0022-1007 $30.00
© 2007 Bashyam
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FROM THE ARCHIVE

 Michael Bevan: Setting up T cell selection

Hema Bashyam, JEM News Editor

hbashyam{at}rockefeller.edu


ABSTRACT
In the 1970s, Michael Bevan showed that T cells only recognize antigens in cells that have the same type of major histocompatibility complex (MHC) molecule present in the thymus where the T cells mature. His work provided the first clues to how thymic self-MHC molecules select the cells that make up the mature T cell repertoire.


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