Home | Help | Feedback | Subscriptions | Archive | Search | Table of Contents

This Article Full Text Full Text (PDF, 1039K) PPT slides of all figures Alert me when this article is cited Citation Map Services Email this article Similar articles in this journal Similar articles in PubMed Alert me to new content in the JEM Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via CrossRef Citing Articles via Google Scholar Google Scholar Articles by Rudensky, A. Y. Articles by Campbell, D. J. Search for Related Content PubMed PubMed Citation Articles by Rudensky, A. Y. Articles by Campbell, D. J. Related Collections Related Article Social Bookmarking                      What's this?

A.Y.R. is at Howard Hughes Medical Institute, Department of Immunology, University of Washington, Box 357370, Seattle, WA 98195.
D.J.C. is at Department of Immunology, University of Washington, Box 357370, Seattle, WA 98195 and Benaroya Research Institute, Seattle, WA 98101.

CORRESPONDENCE A.Y.R.: aruden{at}u.washington.edu OR D.J.C.: campbell{at}benaroyaresearch.org

Abstract
Regulatory CD4 T (T reg) cells control immune responses to self-antigens and pathogens. However, where T reg cells act to curtail effector T cells in vivo and what stage of effector T cell activation or differentiation is targeted by T reg cells remain unknown. Furthermore, a requirement for direct effector T cell–T reg cell contact in vivo has not been ascertained. Varying answers to these important questions have been provided by several new studies.

CiteULike

Complore

Connotea

Del.icio.us

Digg

Reddit

Technorati

This article has been cited by other articles:

• Fujita, T., Teramoto, K., Ozaki, Y., Hanaoka, J., Tezuka, N., Itoh, Y., Asai, T., Fujino, S., Kontani, K., Ogasawara, K. (2009). Inhibition of Transforming Growth Factor-{beta}-Mediated Immunosuppression in Tumor-Draining Lymph Nodes Augments Antitumor Responses by Various Immunologic Cell Types. Cancer Res. 69: 5142-5150 [Abstract] [Full Text]  
• Weaver, J. M., Chaves, F. A., Sant, A. J. (2009). Abortive activation of CD4 T cell responses during competitive priming in vivo. Proc. Natl. Acad. Sci. USA 106: 8647-8652 [Abstract] [Full Text]  
• Cabrera, G., Burzyn, D., Mundinano, J., Courreges, M. C., Camicia, G., Lorenzo, D., Costa, H., Ross, S. R., Nepomnaschy, I., Piazzon, I. (2008). Early Increases in Superantigen-Specific Foxp3+ Regulatory T Cells during Mouse Mammary Tumor Virus Infection. J. Virol. 82: 7422-7431 [Abstract] [Full Text]  
• Correale, P., Tagliaferri, P., Fioravanti, A., Del Vecchio, M. T., Remondo, C., Montagnani, F., Rotundo, M. S., Ginanneschi, C., Martellucci, I., Francini, E., Cusi, M. G., Tassone, P., Francini, G. (2008). Immunity Feedback and Clinical Outcome in Colon Cancer Patients Undergoing Chemoimmunotherapy with Gemcitabine + FOLFOX followed by Subcutaneous Granulocyte Macrophage Colony-Stimulating Factor and Aldesleukin (GOLFIG-1 Trial). Clin. Cancer Res. 14: 4192-4199 [Abstract] [Full Text]  
• Lau, A. W. T., Biester, S., Cornall, R. J., Forrester, J. V. (2008). Lipopolysaccharide-Activated IL-10-Secreting Dendritic Cells Suppress Experimental Autoimmune Uveoretinitis by MHCII-Dependent Activation of CD62L-Expressing Regulatory T Cells. J. Immunol. 180: 3889-3899 [Abstract] [Full Text]  
• Nesburn, A. B., Bettahi, I., Dasgupta, G., Chentoufi, A. A., Zhang, X., You, S., Morishige, N., Wahlert, A. J., Brown, D. J., Jester, J. V., Wechsler, S. L., BenMohamed, L. (2007). Functional Foxp3+ CD4+ CD25(Bright+) "Natural" Regulatory T Cells Are Abundant in Rabbit Conjunctiva and Suppress Virus-Specific CD4+ and CD8+ Effector T Cells during Ocular Herpes Infection. J. Virol. 81: 7647-7661 [Abstract] [Full Text]  
• O'Connor, R. A., Malpass, K. H., Anderton, S. M. (2007). The Inflamed Central Nervous System Drives the Activation and Rapid Proliferation of Foxp3+ Regulatory T Cells. J. Immunol. 179: 958-966 [Abstract] [Full Text]  
• Rudge, G., Barrett, S. P., Scott, B., van Driel, I. R. (2007). Infiltration of a Mesothelioma by IFN-{gamma}-Producing Cells and Tumor Rejection after Depletion of Regulatory T Cells. J. Immunol. 178: 4089-4096 [Abstract] [Full Text]  
• Garcia, Z., Pradelli, E., Celli, S., Beuneu, H., Simon, A., Bousso, P. (2007). Competition for antigen determines the stability of T cell-dendritic cell interactions during clonal expansion. Proc. Natl. Acad. Sci. USA 104: 4553-4558 [Abstract] [Full Text]  
• Hubeau, C., Apostolou, I., Kobzik, L. (2007). Targeting of CD25 and Glucocorticoid-Induced TNF Receptor Family-Related Gene-Expressing T Cells Differentially Modulates Asthma Risk in Offspring of Asthmatic and Normal Mother Mice. J. Immunol. 178: 1477-1487 [Abstract] [Full Text]  
• Rudensky, A. Y., Campbell, D. J. (2006). In vivo sites and cellular mechanisms of T reg cell-mediated suppression. JCB 172: i16-i16 [Full Text]  

Home | Help | Feedback | Subscriptions | Archive | Search

TABLE OF CONTENTS