The Journal of Experimental Medicine
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Published 2 May 2005. doi:10.1084/jem.2019fta
Rockefeller University Press, 0022-1007 $8.00
JEM, Volume 201, Number 9, 1351-1351
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FROM THE ARCHIVE

Harry Goldblatt and the discovery of renin

Heather L. Van Epps

JEM News Editor


Abstract
In 1934, pathologist Harry Goldblatt established the first animal model of hypertension. This model provided researchers with the tools to delineate the renin-angiotensin system of blood pressure control and, eventually, to design enzyme inhibitors for the treatment of chronic hypertension.



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