Autoantibodies against the multicatalytic proteinase in patients with systemic lupus erythematosus

doi:10.1084/jem.173.2.423

This Article

	Full Text (PDF, 904K)
	Alert me when this article is cited
	Citation Map

Services

	Email this article
	Similar articles in this journal
	Similar articles in PubMed
	Alert me to new content in the JEM
	Download to citation manager

Citing Articles

	Citing Articles via HighWire
	Citing Articles via CrossRef
	Citing Articles via Google Scholar

Google Scholar

	Articles by Arribas, J.
	Articles by Castano, J. G.
	Search for Related Content

PubMed

	PubMed Citation
	Articles by Arribas, J.
	Articles by Castano, J. G.


Social Bookmarking

	What's this?

ARTICLES

Autoantibodies against the multicatalytic proteinase in patients with systemic lupus erythematosus

J Arribas, M Luz Rodriguez, R Alvarez-Do Forno and JG Castano
Departamento de Bioquimica, Facultad de Medicina de la UAM, Spain.

Sera from patients with systemic lupus erythematosus contain specific autoantibodies directed against different polypeptide components of the multicatalytic proteinase (also known as proteasome or prosome). These human autoantibodies, in contrast to polyclonal antibodies obtained in rabbits against the purified enzyme, recognize highly conserved epitopes of the multicatalytic proteinase polypeptides from yeast to human.
Add to CiteULike CiteULike Add to Complore Complore Add to Connotea Connotea Add to Del.icio.us Del.icio.us Add to Digg Digg Facebook Add to Reddit Reddit Add to Technorati Technorati Twitter What's this?

This article has been cited by other articles:

Majetschak, M., Perez, M., Sorell, L. T., Lam, J., Maldonado, M. E., Hoffman, R. W. (2008). Circulating 20S Proteasome Levels in Patients with Mixed Connective Tissue Disease and Systemic Lupus Erythematosus. CVI 15: 1489-1493 [Abstract] [Full Text]
Scheffler, S., Kuckelkorn, U., Egerer, K., Dorner, T., Reiter, K., Soza, A., Burmester, G.-R., Feist, E. (2008). Autoimmune reactivity against the 20S-proteasome includes immunosubunits LMP2 ({beta}1i), MECL1 ({beta}2i) and LMP7 ({beta}5i). Rheumatology (Oxford) 47: 622-626 [Abstract] [Full Text]
Feist, E, Brychcy, M, Hausdorf, G, Hoyer, B, Egerer, K, Dorner, T, Kuckelkorn, U, Burmester, G-R (2007). Anti-proteasome autoantibodies contribute to anti-nuclear antibody patterns on human larynx carcinoma cells. Ann Rheum Dis 66: 5-11 [Abstract] [Full Text]
Krause, S, Kuckelkorn, U, Dorner, T, Burmester, G-R, Feist, E, Kloetzel, P-M (2006). Immunoproteasome subunit LMP2 expression is deregulated in Sjogren's syndrome but not in other autoimmune disorders. Ann Rheum Dis 65: 1021-1027 [Abstract] [Full Text]
Mayo, I., Arribas, J., Villoslada, P., Alvarez DoForno, R., Rodriguez-Vilarino, S., Montalban, X., de Sagarra, M. R., Castano, J. G. (2002). The proteasome is a major autoantigen in multiple sclerosis. Brain 125: 2658-2667 [Abstract] [Full Text]
Rodriguez-Vilarino, S., Arribas, J., Arizti, P., Castano, J. G. (2000). Proteolytic Processing and Assembly of the C5 Subunit into the Proteasome Complex. J. Biol. Chem. 275: 6592-6599 [Abstract] [Full Text]
Mengual, E., Arizti, P., Rodrigo, J., Gimenez-Amaya, J. M., Castano, J. G. (1996). Immunohistochemical Distribution and Electron Microscopic Subcellular Localization of the Proteasome in the Rat CNS. J. Neurosci. 16: 6331-6341 [Abstract] [Full Text]