The Journal of Experimental Medicine
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The Journal of Experimental Medicine, Vol 17, 424-428, Copyright, 1913, by The Rockefeller Institute for Medical Research New York

ARTICLE

THE REACTION OF THE LUNGS TO THE INTRABRONCHIAL INSUFFLATION OF KILLED VIRULENT PNEUMOCOCCI AND OF PLAIN STERILE BOUILLON

Martha Wollstein M.D.1 and S. J. Meltzer M.D.1

1 From the Laboratories of The Rockefeller Institute for Medical Research, New York.

The experiments show that intrabronchial insufflation of a culture of virulent pneumococcus killed by heat and still containing stainable organisms produces an inextensive, mild, patchy, superficial inflammation of the lung tissue bearing no similarity to the lesions produced by the living pneumococcus, and that insufflation of sterile bouillon causes a pronounced congestion of the lung tissue with which it comes in contact, sometimes lasting for forty-eight hours.

Submitted on January 9, 1913


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