Recombinant human interleukin 5 is a selective activator of human eosinophil function

doi:10.1084/jem.167.1.219

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Recombinant human interleukin 5 is a selective activator of human eosinophil function

AF Lopez, CJ Sanderson, JR Gamble, HD Campbell, IG Young and MA Vadas
Division of Human Immunology, Institute of Medical and Veterinary Science, Adelaide, South Australia.

Human rIL-5 was found to selectively stimulate morphological changes and the function of human eosinophils. This molecule is thus a prime candidate for the selective eosinophilia and eosinophil activation seen in disease.
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