Journal of Experimental Medicine, Vol 166, 1603-1608, Copyright © 1987 by Rockefeller University Press

ARTICLES

An intermediate cell in thymocyte differentiation that expresses CD8 but not CD4 antigen

DJ Paterson and AF Williams
Medical Research Council Cellular Immunology Unit, Sir William Dunn School of Pathology, University of Oxford, United Kingdom.

Thymocytes of CD4-,CD8+,OX-44- phenotype have been shown to be an intermediate of thymopoiesis that give rise to cells of CD4+, CD8+, OX- 44- normal cortical thymocyte phenotype both in vitro and in vivo during thymic regeneration.
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