Specific cytotoxic T cells are found in the nonrejected kidneys of blood-transfused rats

doi:10.1084/jem.165.2.566

This Article

Full Text (PDF, 384K)

Alert me when this article is cited

Citation Map

Services

Email this article

Similar articles in this journal

Similar articles in PubMed

Alert me to new content in the JEM

Download to citation manager

Citing Articles

Citing Articles via HighWire

Citing Articles via CrossRef

Citing Articles via Google Scholar

Google Scholar

Articles by Dallman, M. J.

Articles by Morris, P. J.

Search for Related Content

PubMed

PubMed Citation

Articles by Dallman, M. J.

Articles by Morris, P. J.

Pubmed/NCBI databases

Medline Plus Health Information
Blood Transfusion and Donation
Kidney Transplantation

Social Bookmarking

What's this?

ARTICLES

Specific cytotoxic T cells are found in the nonrejected kidneys of blood-transfused rats

MJ Dallman, KJ Wood and PJ Morris

Preoperative, donor-specific blood transfusion leads to indefinite survival of rat renal allografts in the strain combinations used. 51Cr- release assays have shown that the level of specific cytotoxic effector activity in the grafts of transfused (nonrejected kidney) animals is very high and may equal or exceed that seen in the grafts of untreated (rejected kidney) recipients. Such cytotoxicity demonstrates specificity for the alloantigens of the kidney, is T cell-mediated, and may persist within the transplant.
Add to CiteULike CiteULike Add to Complore Complore Add to Connotea Connotea Add to Del.icio.us Del.icio.us Add to Digg Digg Facebook Add to Reddit Reddit Add to Technorati Technorati Twitter What's this?

This article has been cited by other articles:

Kataoka, M., Margenthaler, J. A., Ku, G., Flye, M. W. (2003). Development of Infectious Tolerance After Donor-Specific Transfusion and Rat Heart Transplantation. J. Immunol. 171: 204-211 [Abstract] [Full Text]
Young, K. J., Yang, L., Phillips, M. J., Zhang, L. (2002). Donor-lymphocyte infusion induces transplantation tolerance by activating systemic and graft-infiltrating double-negative regulatory T cells. Blood 100: 3408-3414 [Abstract] [Full Text]
Guillet, M., Brouard, S., Gagne, K., Sebille, F., Cuturi, M.-C., Delsuc, M.-A., Soulillou, J.-P. (2002). Different Qualitative and Quantitative Regulation of V{beta} TCR Transcripts During Early Acute Allograft Rejection and Tolerance Induction. J. Immunol. 168: 5088-5095 [Abstract] [Full Text]
Zhou, J., Carr, R. I., Liwski, R. S., Stadnyk, A. W., G. Lee, T. D. (2001). Oral Exposure to Alloantigen Generates Intragraft CD8+ Regulatory Cells. J. Immunol. 167: 107-113 [Abstract] [Full Text]
Spriewald, B. M., Hara, M., Bushell, A., Jenkins, S., Morris, P. J., Wood, K. J. (2000). Differential Role for Competitive Reverse Transcriptase-Polymerase Chain Reaction and Intracellular Cytokine Staining as Diagnostic Tools for the Assessment of Intragraft Cytokine Profiles in Rejecting and Nonrejecting Heart Allografts. Am. J. Pathol. 157: 1453-1458 [Abstract] [Full Text]
Coulombe, M., Yang, H., Wolf, L. A., Gill, R. G. (1999). Tolerance to Antigen-Presenting Cell-Depleted Islet Allografts Is CD4 T Cell Dependent. J. Immunol. 162: 2503-2510 [Abstract] [Full Text]
ROSSINI, A. A., GREINER, D. L., MORDES, J. P. (1999). Induction of Immunologic Tolerance for Transplantation. Physiol. Rev. 79: 99-141 [Abstract] [Full Text]
Josien, R., Heslan, M., Brouard, S., Soulillou, J.-P., Cuturi, M.-C. (1998). Critical Requirement for Graft Passenger Leukocytes in Allograft Tolerance Induced by Donor Blood Transfusion. Blood 92: 4539-4544 [Abstract] [Full Text]