The Journal of Experimental Medicine
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Journal of Experimental Medicine, Vol 164, 962-967, Copyright © 1986 by Rockefeller University Press

ARTICLES

Self-sparing of long-term in vitro-cloned or uncloned cytotoxic T lymphocytes

MF Luciani, JF Brunet, M Suzan, F Denizot and P Golstein

At least some long-term in vitro-cultured cytotoxic T cell clones and uncloned cell populations are able, in the presence of Con A, to lyse other cells, to be lysed by other cells, but not to lyse themselves. This as-yet-unexplained result may have implications as to the mechanism of T cell-mediated cytotoxicity.
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