The Journal of Experimental Medicine
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Journal of Experimental Medicine, Vol 163, 1589-1594, Copyright © 1986 by Rockefeller University Press

ARTICLES

Newcastle disease virus-infected splenocytes express the proopiomelanocortin gene

HJ Westly, AJ Kleiss, KW Kelley, PK Wong and PH Yuen

Infection of murine splenocytes with Newcastle disease virus results in expression of the proopiomelanocortin gene as determined by dot and northern blot analysis of total cellular and poly(A)+ cytoplasmic RNA. These data provide the first evidence that the precursor protein for adrenocorticotropin and beta-endorphin can be synthesized by lymphoid cells.
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