Compartmentalized regulation of macrophage arachidonic acid metabolism

doi:10.1084/jem.163.3.752

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Compartmentalized regulation of macrophage arachidonic acid metabolism

AO Fels, NA Pawlowski, EL Abraham and ZA Cohn

We show that downregulation of arachidonic acid (20:4) metabolism which occurs following i.p. injection of C. parvum can occur in a single, localized macrophage population, and is therefore unlikely to be mediated solely by a systemic factor.
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