Expression of interleukin 2 receptors and binding of interleukin 2 by gamma interferon-induced human leukemic and normal monocytic cells

doi:10.1084/jem.162.3.1111

This Article

	Full Text (PDF, 501K)
	Alert me when this article is cited
	Citation Map

Services

	Email this article
	Similar articles in this journal
	Similar articles in PubMed
	Alert me to new content in the JEM
	Download to citation manager

Citing Articles

	Citing Articles via HighWire
	Citing Articles via CrossRef
	Citing Articles via Google Scholar

Google Scholar

	Articles by Herrmann, F.
	Articles by Griffin, J. D.
	Search for Related Content

PubMed

	PubMed Citation
	Articles by Herrmann, F.
	Articles by Griffin, J. D.


Social Bookmarking

	What's this?

ARTICLES

Expression of interleukin 2 receptors and binding of interleukin 2 by gamma interferon-induced human leukemic and normal monocytic cells

F Herrmann, SA Cannistra, H Levine and JD Griffin

Gamma interferon induced surface expression of interleukin 2 (IL-2) receptors on normal human monocytes and the monocytoid cell lines U937 and HL60. These receptors were detected by anti-IL-2 receptor monoclonal antibodies, and U937 IL-2 receptors were indistinguishable from T lymphocyte IL-2 receptors by immunoprecipitation. Also, U937 IL- 2 receptors bound biologically active IL-2. These results suggest a role for monocyte IL-2 receptors in T cell/monocyte interaction during an immune response.
Add to CiteULike CiteULike Add to Complore Complore Add to Connotea Connotea Add to Del.icio.us Del.icio.us Add to Digg Digg Facebook Add to Reddit Reddit Add to Technorati Technorati Twitter What's this?

This article has been cited by other articles:

TCHOU-WONG, K.-M., TANABE, O., CHI, C., YIE, T.-A., ROM, W.�N. (1999). Activation of NF-kappa B in Mycobacterium tuberculosis- induced Interleukin-2 Receptor Expression in Mononuclear Phagocytes. Am. J. Respir. Crit. Care Med. 159: 1323-1329 [Abstract] [Full Text]
Reya, T., Contractor, N. V., Couzens, M. S., Wasik, M. A., Emerson, S. G., Carding, S. R. (1998). Abnormal Myelocytic Cell Development in Interleukin-2 (IL-2)-Deficient Mice: Evidence for the Involvement of IL-2 in Myelopoiesis. Blood 91: 2935-2947 [Abstract] [Full Text]
Inoue, S., Yamashita, A. (1993). The Phenotypic and Functional Changes of Rat Kupffer Cells Cultured with Interleukin-2. Toxicol Pathol 21: 71-80 [Abstract]
Takeshita, T, Asao, H, Ohtani, K, Ishii, N, Kumaki, S, Tanaka, N, Munakata, H, Nakamura, M, Sugamura, K (1992). Cloning of the gamma chain of the human IL-2 receptor. Science 257: 379-382 [Abstract]
Curran, R. D., Billiar, T. R., West, M. A., Bentz, B. G., Simmons, R. L. (1988). Effect of Interleukin 2 on Kupffer Cell Activation: Interleukin 2 Primes and Activates Kupffer Cells to Suppress Hepatocyte Protein Synthesis In Vitro. Arch Surg 123: 1373-1378 [Abstract]
Marcon, L., Rubin, L. A., Kurman, C. C., Fritz, M. E., Longo, D. L., Uchiyama, T., Edwards, B. K., Nelson, D. L. (1988). Elevated Serum Levels of Soluble Tac Peptide in Adult T-Cell Leukemia: Correlation with Clinical Status during Chemotherapy. ANN INTERN MED 109: 274-279 [Abstract]
MURPHY, P. M., LANE, H. C., GALLIN, J. I., FAUCI, A. S. (1988). Marked Disparity in Incidence of Bacterial Infections in Patients with the Acquired Immunodeficiency Syndrome Receiving Interleukin-2 or Interferon-{gamma}. ANN INTERN MED 108: 36-41 [Abstract]