The Journal of Experimental Medicine
VeriKine-HS Human IFN-Beta
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The Journal of Experimental Medicine, Vol 16, 315-324, Copyright, 1912, by The Rockefeller Institute for Medical Research New York


ARTICLE

THE DURATION OF IMMUNE BODIES IN THE BLOOD AFTER ANTITYPHOID INOCULATION

Martha Wollstein M.D.1

1 From the Laboratories of The Rockefeller Institute for Medical Research, New York.

In this series of twenty-four persons inoculated with antityphoid vaccine, the immune bodies in the blood reached their height within two months after the first inoculation, or one month after the third, then fell rapidly within the next two months. Only nineteen of the cases could be followed longer, and eight of these were negative for bactericidins within ten months after inoculation, and fifteen were negative after thirteen months. Only one serum reacted in a dilution of 1 to 1,200 at the end of thirteen months.

The addition of lecithin to the vaccine did not influence the local reaction after inoculation, nor did it appreciably affect the formation of immune bodies to the typhoid bacillus.

Submitted on May 29, 1912


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