The Journal of Experimental Medicine
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The Journal of Experimental Medicine, Vol 16, 249-260, Copyright, 1912, by The Rockefeller Institute for Medical Research New York

ARTICLE

THE NATURE OF THE BACTERICIDAL SUBSTANCE IN LEUCOCYTIC EXTRACT

Wilfred H. Manwaring M.D.1

1 From the Laboratories of The Rockefeller Institute for Medical Research, New York.

1. The bactericidal agent extracted from horse leucocytes is apparently precipitated quantitatively by full saturation with ammonium sulphate.

2. The bactericidal agent is apparently precipitated by absolute alcohol, and is not rendered insoluble by a short contact with alcohol. The agent resembled in this feature certain enzymes which can be isolated and purified by alcoholic precipitation.

 Submitted on May 9, 1912


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