Surface antigens of melanocytes and melanomas. Markers of melanocyte differentiation and melanoma subsets

doi:10.1084/jem.156.6.1755

This Article

	Full Text (PDF, 1800K)
	Alert me when this article is cited
	Citation Map

Services

	Email this article
	Similar articles in this journal
	Similar articles in PubMed
	Alert me to new content in the JEM
	Download to citation manager

Citing Articles

	Citing Articles via HighWire
	Citing Articles via CrossRef
	Citing Articles via Google Scholar

Google Scholar

	Articles by Houghton, A. N.
	Articles by Old, L. J.
	Search for Related Content

PubMed

	PubMed Citation
	Articles by Houghton, A. N.
	Articles by Old, L. J.


Social Bookmarking

	What's this?

ARTICLES

Surface antigens of melanocytes and melanomas. Markers of melanocyte differentiation and melanoma subsets

AN Houghton, M Eisinger, AP Albino, JG Cairncross and LJ Old

The surface antigens of melanocytes from newborn and adult skin have been analyzed with monoclonal antibodies detecting cell surface antigens of malignant melanoma. Antigenic markers that distinguish early, intermediate, and mature stages in melanocyte differentiation have been defined. The characteristics of the normal melanocyte precursor have been inferred from the features of melanomas that express early markers of melanocyte differentiation. A rudimentary surface antigen map of cells undergoing melanocyte differentiation and a new classification of melanomas based on the expression of melanocyte differentiation antigens are proposed.
Add to CiteULike CiteULike Add to Complore Complore Add to Connotea Connotea Add to Del.icio.us Del.icio.us Add to Digg Digg Facebook Add to Reddit Reddit Add to Technorati Technorati Twitter What's this?

This article has been cited by other articles:

Sviderskaya, E. V., Easty, D. J., Lawrence, M. A., Sanchez, D. P., Negulyaev, Y. A., Patel, R. H., Anand, P., Korchev, Y. E., Bennett, D. C. (2009). Functional neurons and melanocytes induced from immortal lines of postnatal neural crest-like stem cells. FASEB J. 23: 3179-3192 [Abstract] [Full Text]
Eslami, A., Gallant-Behm, C. L., Hart, D. A., Wiebe, C., Honardoust, D., Gardner, H., Hakkinen, L., Larjava, H. S. (2009). Expression of Integrin {alpha}v{beta}6 and TGF-{beta} in Scarless vs Scar-forming Wound Healing. J. Histochem. Cytochem. 57: 543-557 [Abstract] [Full Text]
Kiewe, P, Bechrakis, N., Schmittel, A, Ruf, P, Lindhofer, H, Thiel, E, Nagorsen, D (2006). Increased chondroitin sulphate proteoglycan expression (B5 immunoreactivity) in metastases of uveal melanoma. Ann Oncol 17: 1830-1834 [Abstract] [Full Text]
Perales, M.-A., Diab, A., Cohen, A. D., Huggins, D. W., Guevara-Patino, J. A., Hubbard, V. M., Engelhorn, M. E., Kochman, A. A., Eng, J. M., Mortazavi, F., Alpdogan, O., Terwey, T. H., Heller, G., Wolchok, J. D., Houghton, A. N., van den Brink, M. R. M. (2006). DNA Immunization against Tissue-Restricted Antigens Enhances Tumor Immunity after Allogeneic Hemopoietic Stem Cell Transplantation. J. Immunol. 177: 4159-4167 [Abstract] [Full Text]
Goldberg, S. M., Bartido, S. M., Gardner, J. P., Guevara-Patino, J. A., Montgomery, S. C., Perales, M.-A., Maughan, M. F., Dempsey, J., Donovan, G. P., Olson, W. C., Houghton, A. N., Wolchok, J. D. (2005). Comparison of Two Cancer Vaccines Targeting Tyrosinase: Plasmid DNA and Recombinant Alphavirus Replicon Particles. Clin. Cancer Res. 11: 8114-8121 [Abstract] [Full Text]
Weinreb, P. H., Simon, K. J., Rayhorn, P., Yang, W. J., Leone, D. R., Dolinski, B. M., Pearse, B. R., Yokota, Y., Kawakatsu, H., Atakilit, A., Sheppard, D., Violette, S. M. (2004). Function-blocking Integrin {alpha}v{beta}6 Monoclonal Antibodies: DISTINCT LIGAND-MIMETIC AND NONLIGAND-MIMETIC CLASSES. J. Biol. Chem. 279: 17875-17887 [Abstract] [Full Text]
Gold, J. S., Ferrone, C. R., Guevara-Patino, J. A., Hawkins, W. G., Dyall, R., Engelhorn, M. E., Wolchok, J. D., Lewis, J. J., Houghton, A. N. (2003). A Single Heteroclitic Epitope Determines Cancer Immunity After Xenogeneic DNA Immunization Against a Tumor Differentiation Antigen. J. Immunol. 170: 5188-5194 [Abstract] [Full Text]
Sviderskaya, E. V., Hill, S. P., Evans-Whipp, T. J., Chin, L., Orlow, S. J., Easty, D. J., Cheong, S. C., Beach, D., DePinho, R. A., Bennett, D. C. (2002). p16Ink4a in Melanocyte Senescence and Differentiation. JNCI J Natl Cancer Inst 94: 446-454 [Abstract] [Full Text]
Touab, M., Villena, J., Barranco, C., Arumi-Uria, M., Bassols, A. (2002). Versican Is Differentially Expressed in Human Melanoma and May Play a Role in Tumor Development. Am. J. Pathol. 160: 549-557 [Abstract] [Full Text]
Goodwin, B. L., Xi, H., Tejiram, R., Eason, D. D., Ghosh, N., Wright, K. L., Nagarajan, U., Boss, J. M., Blanck, G. (2001). Varying Functions of Specific Major Histocompatibility Class II Transactivator Promoter III and IV Elements in Melanoma Cell Lines. Cell Growth Differ. 12: 327-335 [Abstract] [Full Text]
Bowne, W. B., Srinivasan, R., Wolchok, J. D., Hawkins, W. G., Blachere, N. E., Dyall, R., Lewis, J. J., Houghton, A. N. (1999). Coupling and Uncoupling of Tumor Immunity and Autoimmunity. JEM 190: 1717-1722 [Abstract] [Full Text]
Wang, S., Bartido, S., Yang, G., Qin, J., Moroi, Y., Panageas, K. S., Lewis, J. J., Houghton, A. N. (1999). A Role for a Melanosome Transport Signal in Accessing the MHC Class II Presentation Pathway and in Eliciting CD4+ T Cell Responses. J. Immunol. 163: 5820-5826 [Abstract] [Full Text]
Wesley, U. V., Albino, A. P., Tiwari, S., Houghton, A. N. (1999). A Role for Dipeptidyl Peptidase IV in Suppressing the Malignant Phenotype of Melanocytic Cells. JEM 190: 311-322 [Abstract] [Full Text]
Giacomini, P., Giorda, E., Fraioli, R., Nicotra, M. R., Vitale, N., Setini, A., Delfino, L., Morabito, A., Benevolo, M., Venturo, I., Mottolese, M., Ferrara, G. B., Natali, P. G. (1999). Low Prevalence of Selective Human Leukocyte Antigen (HLA)-A and HLA-B Epitope Losses in Early-Passage Tumor Cell Lines. Cancer Res. 59: 2657-2667 [Abstract] [Full Text]
Martin, P., Sanes, J. (1997). Integrins mediate adhesion to agrin and modulate agrin signaling. Development 124: 3909-3917 [Abstract]
Naftzger, C., Takechi, Y., Kohda, H., Hara, I., Vijayasaradhi, S., Houghton, A.�N. (1996). Immune response to a differentiation antigen induced by altered antigen: A study of tumor rejection and�autoimmunity. Proc. Natl. Acad. Sci. USA 93: 14809-14814 [Abstract] [Full Text]
Zambruno, G, Marchisio, P., Melchiori, A, Bondanza, S, Cancedda, R, De Luca, M (1993). Expression of integrin receptors and their role in adhesion, spreading and migration of normal human melanocytes. J. Cell Sci. 105: 179-190 [Abstract]
Thomas, L, Chan, P., Chang, S, Damsky, C (1993). 5-Bromo-2-deoxyuridine regulates invasiveness and expression of integrins and matrix-degrading proteinases in a differentiated hamster melanoma cell. J. Cell Sci. 105: 191-201 [Abstract]