Journal of Experimental Medicine, Vol 145, 1066-1070, Copyright © 1977 by Rockefeller University Press

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Molecular similarities between the Qa-2 alloantigen and other gene products of the 17th chromosome of the mouse

J Michaelson, L Flaherty, E Vitetta and MD Poulik

The alloantigen Qa-2, whose gene is located on the 17th chromosome between H-2D and Tla, is identified as a molecule of 43,000 daltons which is associated with beta 2-microglobulin. Qa-2 comprises approximately 0.15% of the iodinateable cell surface protein of lymph node cells. Sequential precipitations demonstrated that Qa-2 is distinct from H-2D and H-2K molecules.
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