The Journal of Experimental Medicine
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Journal of Experimental Medicine, Vol 144, 834-839, Copyright © 1976 by Rockefeller University Press

ARTICLES

Murine t factors: an association between alleles at t and at H-2

JR Levinson and HO McDevitt

Lymphocytes from tx-mutant mice have a definite and consistent pattern of reactivity in MLR. Cells from t-mutant mice within a complementation group usually fail to stimulate each other, while cells from mutants in different complementation groups stimulate each other strongly. This indicates that tx-mutant types are associated with certain H-2 haplotypes, and that members of any give complementation group share the same H-2 haplotype.
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