Autologous stimulation of human lymphocyte subpopulation

doi:10.1084/jem.142.5.1327

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Autologous stimulation of human lymphocyte subpopulation

G Opelz, M Kiuchi, M Takasugi and PI Terasaki

The background stimulation universally seen when lymphocytes are cultured in vitro has been shown to be markedly lowered by reducing the proportion of B lymphocytes. B-rich fractions of lymphocytes had extremely high background stimulation. It is concluded that stimulation of T cells, probably by autologous B cells, provides the most probable explanation for the findings described.
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