The Journal of Experimental Medicine
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Journal of Experimental Medicine, Vol 142, 1312-1315, Copyright © 1975 by Rockefeller University Press

ARTICLES

Cellular basis of tolerance in neonatally induced mouse chimeras

WK Silvers, WL Elkins and FW Quimby

In mice, thymectomized as young adults, neonatally induced tolerance persists in the putative absence of cell chimerism. The finding provides evidence that a selective deficiency of specific clones of lymphocytes exists in transplantation tolerance when induced under the conditions of these experiments.
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