The Journal of Experimental Medicine
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Journal of Experimental Medicine, Vol 142, 1011-1016, Copyright © 1975 by Rockefeller University Press

ARTICLES

Localization of aggregated cell surface antigens of target cells bound to cytotoxic T lymphocytes

G Berke and ZV Fishelson

The redistribution of aggregated cell surface antigens of target cells bound to cytotoxic T lymphocytes was investigated. It was found that cap formation induced by antibody always occurred toward the site of binding. It is suggested that the polar localization of capped target cell surface determinants is a consequence of cytotoxic T-lymphocyte target cell interaction.
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