The Journal of Experimental Medicine
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Journal of Experimental Medicine, Vol 142, 536-541, Copyright © 1975 by Rockefeller University Press

ARTICLES

Transplantation behavior of A.TH and A.TL T-cell lymphomas in congenic resistant and hybrid strains

JW Goding and NL Warner

Seven spontaneously arising T-cell lymphomas originating in A.TH or A.TL mice, which are congenic for the immune response gene (I) chromosomal segment were described. When transplanted into partner strains which were incompatible at the I region, the tumors were rapidly rejected. Rejection was proposed to be due to the presence of antigens controlled by I-region genes.
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