The Journal of Experimental Medicine
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The Journal of Experimental Medicine, Vol 139, 13-23, Copyright © 1974 by The Rockefeller University Press

ARTICLE

THE THYMIC SUPPRESSOR CELL : I. SEPARATION OF SUBPOPULATIONS WITH SUPPRESSOR ACTIVITY



Tai-You Ha 1, Byron H. Waksman 1, and H. Peter Treffers 1

1 From the Department of Microbiology, Yale University, New Haven, Connecticut 06510

This study confirms the finding that washed thymocytes from rats given 100 mg of BGG 48 h earlier, when transferred to syngeneic recipients, exert a specific suppressor effect on immunological responses to BGG in the latter. The active cells are found in a subpopulation of low density, making up less than 10% of the total thymocytes, and are partially resistant to hydrocortisone.

Submitted on August 23, 1973


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