The Journal of Experimental Medicine
VeriKine-HS Human IFN-Beta
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The Journal of Experimental Medicine, Vol 137, 1091-1096, Copyright © 1973 by The Rockefeller University Press

BRIEF DEFINITIVE REPORTS

INDUCTION OF ARGINASE ACTIVITY WITH THE SHOPE PAPILLOMA VIRUS IN TISSUE CULTURE CELLS FROM AN ARGININEMIC PATIENT

Stanfield Rogers 1, A. Lowenthal 1, H. G. Terheggen 1, and J. P. Columbo 1

1 From the Biology Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee 37830, Foundation Born-Bunge, Antwerp, Belgium, Kinderkrankenhaus, Cologne, West Germany, and Inselspital Bern, Chemisches Zentrallabor, Bern, Switzerland

Inoculation of the Shope virus in tissue cultures of human fibroblasts from a patient with a deficiency of the enzyme arginase results in an induction of arginase activity, apparently virus coded.

Submitted on October 20, 1972


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