The Journal of Experimental Medicine
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The Journal of Experimental Medicine, Vol 110, 571-584, Copyright, 1959, by The Rockefeller Institute

ARTICLE

SIMULTANEOUS PRODUCTION OF TWO CAPSULAR POLYSACCHARIDES BY PNEUMOCOCCUS : I. PROPERTIES OF A PNEUMOCOCCUS MANIFESTING BINARY CAPSULATION



Robert Austrian M.D.1 and Harriet P. Bernheimer Ph.D.1

1 From the Department of Medicine, State University of New York College of Medicine at New York City, Brooklyn

Pneumococci manifesting binary capsulation have been produced through the agency of transformation reactions. Such cells produce two capsular polysaccharides which are closely similar if not identical with those produced by corresponding singly capsulated strains.

Binary capsulation in pneumococcus provides a new basis for serologic cross-reactivity in this species.

 Submitted on June 4, 1959


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